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1

Indole-3-carbinol as a chemopreventive and anti-cancer agent

Jing-Ru Weng, Chen-Hsun Tsai, Samuel K. Kulp, Ching-Shih Chen

Journal:

Year:

2008

Language:

english

File:

PDF, 551 KB

english, 2008

2

A Novel Dual AMPK Activator/mTOR Inhibitor Inhibits Thyroid Cancer Cell Growth

Plews, Robert L., Mohd Yusof, Adlina, Wang, Chaojie, Saji, Motoyasu, Zhang, Xiaoli, Chen, Ching-Shih, Ringel, Matthew D., Phay, John E.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2015

Language:

english

File:

PDF, 2.38 MB

english, 2015

3

Enzymatic catalysis in cosolvent modified pressurized organic solvents

Marazban Sarkari, Barbara L. Knutson, Ching-Shih Chen

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 154 KB

english, 1999

4

CD72-mediated B cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3-kinase

Chandrasekar Venkataraman, Pei-Jung Lu, Anne Mette Buhl, Ching-Shih Chen, John C. Cambier, Subbarao Bondada

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 206 KB

english, 1998

5

Mikrobielle asymmetrische Katalyse — enantioselektive Reduktion von Ketonen

Prof. Charles J. Sih, Ching-Shih Chen

Journal:

Angewandte Chemie

Year:

1984

Language:

german

File:

PDF, 918 KB

german, 1984

6

Enantioselektive Biokatalyse in organischen Solventien am Beispiel Lipase-katalysierter Reaktionen

Prof. Dr. Ching-Shih Chen, Prof. Dr. Charles J. Sih

Journal:

Angewandte Chemie

Year:

1989

Language:

german

File:

PDF, 1.32 MB

german, 1989

7

Microbial Asymmetric Catalysis—Enantioselective Reduction of Ketones [New Synthetic Methods (45)]

Prof. Charles J. Sih, Ching-Shih Chen

Journal:

Angewandte Chemie International Edition

Year:

1984

Language:

english

File:

PDF, 847 KB

english, 1984

8

General Aspects and Optimization of Enantioselective Biocatalysis in Organic Solvents: The Use of Lipases [New Synthetic Methods (76)]

Prof. Ching-Shih Chen, Prof. Charles J. Sih

Journal:

Angewandte Chemie International Edition

Year:

1989

Language:

english

File:

PDF, 1.24 MB

english, 1989

9

Efficacy of a novel histone deacetylase inhibitor in murine models of hepatocellular carcinoma

Yen-Shen Lu, Yoko Kashida, Samuel K. Kulp, Yu-Chieh Wang, Dasheng Wang, Jui-Hsiang Hung, Monica Tang, Zhong-Zhe Lin, Te-Jung Chen, Ann-Lii Cheng, Ching-Shih Chen

Journal:

Year:

2007

Language:

english

File:

PDF, 2.72 MB

english, 2007

10

Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells

Mei-Chuan Chen, Chun-Han Chen, Hsiao-Ching Chuang, Samuel K. Kulp, Che-Ming Teng, Ching-Shih Chen

Journal:

Year:

2011

Language:

english

File:

PDF, 2.47 MB

english, 2011

11

Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9

Haiming Ding, Chunhua Han, Jiuxiang Zhu, Ching-Shih Chen, Steven M. D'Ambrosio

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 302 KB

english, 2005

12

Increased PTEN expression due to transcriptional activation of PPARγ by Lovastatin and Rosiglitazone

Rosemary E. Teresi, Chung-Wai Shaiu, Ching-Shih Chen, V. Krishna Chatterjee, Kristin A. Waite, Charis Eng

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

13

Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21WAF1/CIP1 dependent

Haiming Ding, Chunhua Han, Dongmei Guo, Dasheng Wang, Wenrui Duan, Ching-Shih Chen, Steven M. D'Ambrosio

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 474 KB

english, 2008

14

OSU03012 activates Erk1/2 and Cdks leading to the accumulation of cells in the S-phase and apoptosis

Haiming Ding, Chunhua Han, Dongmei Guo, Dasheng Wang, Ching-Shih Chen, Steven M. D'Ambrosio

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 529 KB

english, 2008

15

The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells

Shuhong Zhang, Attaya Suvannasankha, Colin D. Crean, Valerie L. White, Ching-Shih Chen, Sherif S. Farag

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

16

Preparation of enantiomerically-active deuterium-labelled ibuprofen

Ching-Shih Chen, Debra Copeland, Shawn Harriman, Yeuk-Cheun Liu

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1990

Language:

english

File:

PDF, 348 KB

english, 1990

17

Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas

Abraham Jacob, Janet Oblinger, Matthew L. Bush, Victoria Brendel, Griffin Santarelli, Abhik R. Chaudhury, Samuel Kulp, Krista M. D. La Perle, Ching-Shih Chen, Long-Sheng Chang, D. Bradley Welling

Journal:

The Laryngoscope

Year:

2012

Language:

english

File:

PDF, 11.63 MB

english, 2012

18

Targeting histone deacetylase in cancer therapy

Hsiang-Yu Lin, Chang-Shi Chen, Shuan-Pei Lin, Jing-Ru Weng, Ching-Shih Chen

Journal:

Medicinal Research Reviews

Year:

2006

Language:

english

File:

PDF, 442 KB

english, 2006

19

Biotinylated Phosphatidylinositol 3,4,5-Trisphosphate as Affinity Ligand

Da-Sheng Wang, Tsui-Ting Ching, Jan St. Pyrek, Ching-Shih Chen

Journal:

Analytical Biochemistry

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

20

An efficient chemoenzymic access to optically active myo-inositol polyphosphates

Da-Ming Gou, Yeuk-Chuen Liu, Ching-Shih Chen

Journal:

Carbohydrate Research

Year:

1992

Language:

english

File:

PDF, 985 KB

english, 1992

21

Stereochemical control of yeast reductions. 2. Quantitative treatment of the kinetics of competing enzyme systems for a single substrate

Ching-Shih Chen, Bing-nan Zhou, Gary Girdaukas, Woan-Ru Shieh, Frank VanMiddlesworth, Aravamudan S. Gopalan, Charles J. Sih

Journal:

Bioorganic Chemistry

Year:

1984

Language:

english

File:

PDF, 1020 KB

english, 1984

22

A Structurally Optimized Celecoxib Derivative Inhibits Human Pancreatic Cancer Cell Growth

Junan Li, Jiuxiang Zhu, W. Scott Melvin, Tanios S. Bekaii-Saab, Ching-Shih Chen, Peter Muscarella

Journal:

Journal of Gastrointestinal Surgery

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006

23

L-carnitine via enzyme-catalyzed oxidative kinetic resolution

Dennis Ditullio, David Anderson, Ching-Shih Chen, Charles J. Sih

Journal:

Bioorganic & Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.47 MB

english, 1994

24

The inhibition of osteogenesis with human bone marrow mesenchymal stem cells by CdSe/ZnS quantum dot labels

Shu-Chen Hsieh, Fung-Fang Wang, Ching-Shih Lin, Yu-Ju Chen, Shih-Chieh Hung, Yng-Jiin Wang

Journal:

Year:

2006

Language:

english

File:

PDF, 608 KB

english, 2006

25

Determination of esterase activity of papain by high-performance liquid chromatography

Ching-Shih Chen, Shih-Hsiung Wu, Kung-Tsung Wang

Journal:

Journal of Chromatography A

Year:

1982

Language:

english

File:

PDF, 295 KB

english, 1982

26

An efficient route toD-myo-inositol 1,3,4-triphosphate andD-myo-inositol 1,3,4,5-tetrakisphosphate

Da-Ming Gou, Ching-Shih Chen

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 194 KB

english, 1992

27

Bifunctional chiral synthons via biochemical methods. : VII. Optically-active 2.2′-dihydroxy-1,1′-binaphthyl.

Shih-Hsiung Wu, Li-Qing Zhang, Ching-Shih Chen, Gary Girdaukas, C.J. Sih

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 199 KB

english, 1985

28

An efficient synthesis of optically active D-myo-inositol 1,4,5-triphosphate

Yeuk-Chuen Liu, Ching-Shih Chen

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 261 KB

english, 1989

29

A chemoenzymatic access to optically active 1,2-epoxides

Ching-Shih Chen, Yeuk-Chuen Liu

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 241 KB

english, 1989

30

A phosphatidylinositol 3,4,5-trisphosphate analogue with low serum protein-binding affinity

Da-Sheng Wang, Ao-Lin Hsu, Ching-Shih Chen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 236 KB

english, 2001

31

d-myo-Inositol 1,4,5-trisphosphate analogues as useful tools in biochemical studies of intracellular calcium mobilization

Da-Ming Gou, Woan-Ru Shieh, Pei-Jung Lu, Ching-Shih Chen

Journal:

Bioorganic & Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 703 KB

english, 1994

32

Eradication of intracellularFrancisella tularensisin THP-1 human macrophages with a novel autophagy inducing agent

Hao-Chieh Chiu, Shilpa Soni, Samuel K Kulp, Heather Curry, Dasheng Wang, John S Gunn, Larry S Schlesinger, Ching-Shih Chen

Journal:

Journal of Biomedical Science

Year:

2009

Language:

english

File:

PDF, 665 KB

english, 2009

33

Identification of novel DNA methylation inhibitors via a two-component reporter gene system

Yi-Shiuan Lin, Arthur Y Shaw, Shi-Gang Wang, Chia-Chen Hsu, I-Wen Teng, Min-Jen Tseng, Tim HM Huang, Ching-Shih Chen, Yu-Wei Leu, Shu-Huei Hsiao

Journal:

Journal of Biomedical Science

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

34

Biocatalytic resolution of DL-propranolol. A successful example of computer-aided substrate design

Ching-Shih Chen, Da-Ming Gou, Woan-Ru Shieh, Yeuk-Chuen Liu

Journal:

Year:

1993

Language:

english

File:

PDF, 642 KB

english, 1993

35

Synthesis and biological evaluation of l-α-Phosphatidyl-d-3-deoxy-3-heteromethyl-myo-inositols as phosphoinositide 3-kinase inhibitors

Da-Sheng Wang, Ching-Shih Chen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 237 KB

english, 2001

36

The humanized CD40 antibody SGN-40 demonstrates pre-clinical activity that is enhanced by lenalidomide in chronic lymphocytic leukaemia

Rosa Lapalombella, Aruna Gowda, Trupti Joshi, Najma Mehter, Carolyn Cheney, Amy Lehman, Ching-Shih Chen, Amy J. Johnson, Michael A. Caligiuri, Susheela Tridandapani, Natarajan Muthusamy, John C. Byrd

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 253 KB

english, 2009

37

OSU-DY7, a novel D-tyrosinol derivative, mediates cytotoxicity in chronic lymphocytic leukaemia and Burkitt lymphoma through p38 mitogen-activated protein kinase pathway

Li-Yuan Bai, Yihui Ma, Samuel K. Kulp, Shu-Huei Wang, Chang-Fang Chiu, Frank Frissora, Rajeswaran Mani, Xiaokui Mo, David Jarjoura, John C. Byrd, Ching-Shih Chen, Natarajan Muthusamy

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 598 KB

english, 2011

38

Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity

Tsui-Ting Ching, Wei-Chung Chiang, Ching-Shih Chen, Ao-Lin Hsu

Journal:

Year:

2011

Language:

english

File:

PDF, 544 KB

english, 2011

39

Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent

Hsiang-Yu Lin, Yi-Chiu Kuo, Yu-I Weng, I-Lu Lai, Tim H.-M. Huang, Shuan-Pei Lin, Dau-Ming Niu, Ching-Shih Chen

Journal:

Year:

2012

Language:

english

File:

PDF, 582 KB

english, 2012

40

Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells

Hsiao-Ching Chuang, Naval Kapuriya, Samuel K. Kulp, Ching-Shih Chen, Charles L. Shapiro

Journal:

Breast Cancer Research and Treatment

Year:

2012

Language:

english

File:

PDF, 904 KB

english, 2012

41

Metabolic stereoisomeric inversion of ibuprofen in mammals

Ching-Shih Chen, Woan-Ru Shieh, Pei-Heng Lu, Shawn Harriman, Ching-Yu Chen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1991

Language:

english

File:

PDF, 668 KB

english, 1991

42

Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway

Jui-Ling Hsu, Yunn-Fang Ho, Tsai-Kun Li, Ching-Shih Chen, Lih-Ching Hsu, Jih-Hwa Guh

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

43

Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma

Bevin Zimmerman, Aaron Sargeant, Kristina Landes, Soledad A. Fernandez, Ching-Shih Chen, Michael D. Lairmore

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

44

Regulation of protein kinase C ζ by PI 3-kinase and PDK-1

Margaret M. Chou, Weimin Hou, Joanne Johnson, Lauren K. Graham, Mark H. Lee, Ching-Shih Chen, Alexandra C. Newton, Brian S. Schaffhausen, Alex Toker

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 397 KB

english, 1998

45

Synthesis and Biological Evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as Potent Histone Deacetylase Inhibitors with Antitumor Activity in Vivo

Lai, Mei-Jung, Huang, Han-Li, Pan, Shiow-Lin, Liu, Yi-Min, Peng, Chieh-Yu, Lee, Hsueh-Yun, Yeh, Teng-Kuang, Huang, Po-Hsien, Teng, Che-Ming, Chen, Ching-Shih

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.79 MB

english, 2012

46

Antagonistic Effect of Inositol Pentakisphosphate on Inositol Triphosphate Receptors

Pei-Jung Lu, Woan-Ru Shieh, Ching-Shih Chen

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 68 KB

english, 1996

47

Regulation of Nuclear Calcium Uptake by Inositol Phosphates and External Calcium

Ao-Lin Hsu, Pei-Jung Lu, Ching-Shih Chen

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 122 KB

english, 1998

48

Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus

Hao-Chieh Chiu, Su-Lin Lee, Naval Kapuriya, Dasheng Wang, Yi-Ru Chen, Sung-Liang Yu, Samuel K. Kulp, Lee-Jene Teng, Ching-Shih Chen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 688 KB

english, 2012

49

PPARγ-independent antitumor effects of thiazolidinediones

Shuo Wei, Jian Yang, Su-Lin Lee, Samuel K. Kulp, Ching-Shih Chen

Journal:

Year:

2009

Language:

english

File:

PDF, 421 KB

english, 2009

50

Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair

Jui-Ling Hsu, Pui-Kei Leong, Yunn-Fang Ho, Lih-Ching Hsu, Pin-Hsuan Lu, Ching-Shih Chen, Jih-Hwa Guh

Journal:

Year:

2012

Language:

english

File:

PDF, 1008 KB

english, 2012

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